Principal Investigator: Prof. Hüseyin Firat

Firalis is a biotechnology company, creating novel values via biomarker discovery, development and regulatory qualification that ultimately lead to biomarker-based diagnostics.

With a comprehensive expertise in the field, Firalis develops biomarkers and biomarker-based diagnostic kits to improve disease outcomes and patient comfort, increase therapeutic decisions and finally to reduce healthcare costs remarkably, being the principle goals of biomarker services offered by Firalis.
Firalis owes its leading position to a unique network of clinical centers of excellence that it established to conduct studies of biomarker qualification in clinics.

Main tasks within BTCure
(1) Identification of predictive mRNA biomarkers for monitoring treatment response in RA, (2) development of a panel of 45 selected mRNAs Biomarkers for the monitoring of treatment response in RA using IVD HTG Edge technology and (3) performance evaluation of this this panel on Retrospective study for monitoring treatment response in RA.

Primary areas of expertise
Our activities mainly but not exclusively involve biomarkers that are related to disorders including common diseases such as myocardial infarction, hearth failure, rheumatoid arthritis or rare/orphan diseases such as systemic or autoimmune vasculitis. A major part of our activities cover drug-induced organ injuries in particular kidney, liver and vasculature, as major drug targets. For more information please visit our webpage (

Short profile of the main staff involved

Hüseyin FIRAT, MD, PhD; President of Firalis SAS,

Assistant Professor in pediatric hematoimmunlogy (AP-HP). PhD/Research Director (Pasteur Institute/ Généthon). Creator/Head of the x-omics data analysis sections and Senior Member of Innovation Teams (Novartis, 2002-07), Professor of University in France (accredited: 2007), funder president of Firalis SAS since 2008, also President of TcLand Expression SA since July 2013.

Dr. Eric SCHORDAN; Molecular Diagnostic Head at Firalis SAS,

PhD in molecular and cellular biology (University Louis Pasteur, Strasbourg). IEF Marie-Currie fellow (2006-2008) and senior postdoctorant (2009-2013). Molecular Diagnostics Head at Firalis SAS since September 2013.